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Anemia secondary to valproic acid therapy in a 13- year-old boy: a case report
Authors:Barbara Kaczorowska-Hac  Agnieszka Matheisel  Lucyna Maciejka-Kapuscinska  Jakub Wisniewski  Anna Alska  Elzbieta Adamkiewicz-Drozynska  Anna Balcerska  Iwona Reszczynska
Abstract:ABSTRACT: INTRODUCTION: Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among theoccasionally observed adverse effects of this medication. CASE PRESENTATION: We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12months after the introduction of valproic acid therapy. A bone marrow biopsy revealedmaturation arrest of proerythroblasts. CONCLUSION: Prompt diagnosis and valproic acid discontinuation resulted in the patient's recovery.
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