Effects of Antioxidants of Different Nature on Functions of Tissue—Blood Barriers of the Neuroendocrine Center of Wistar White Rats of Both Sexes |
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| Authors: | A. V. Kotel'nikov D. L. Teplyi E. S. Balybin |
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| Affiliation: | (1) Astrakhan State Technical University, Russia;(2) Astrakhan State University, Russia;(3) Research Institute of Leprosy Studies, Russian Federation Ministry of Health, Astrakhan, Russia |
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| Abstract: | Effects of natural (α-tocopherol) and synthetic (ionol) antioxidants on permeability of tissue—blood barriers of the hypothalamus-pituitary system to an alien (the dye neutral red) and physiologically adequate agent (3H-thymidine) were studied in male and female Wistar rats. The antioxidants were established to enhance the protective function of the tissue—blood barriers, especially in females. The permeability to 3H-thymidine in hypothalamus decreased only in males and only after effect of α-tocopherol, whereas in pituitary, in animals of both sexes and especially after action of the bioantioxidant. |
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