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Biosynthesis of antifungal isoflavonoids in Lupinus albus. Enzymatic prenylation of genistein and 2'-hydroxygenistein.
Authors:Gudrun Schröder  Ulrich Zähringer  Werner Heller  Jürgen Ebel  Hans Grisebach
Affiliation:Lehrstuhl für Biochemie der Pflanzen Institut für Biologie II Universität Freiburg, Schänzlestr. 1 D-7800 Freiburg i.Br., Germany
Abstract:A 45,000g particulate fraction from hypocotyls of Lupinus albus catalyzes the prenylation of genistein 1 and 2′-hydroxygenistein 2 with dimethylallyl pyrophosphate to the antifungal 6-isopentenylgenistein 3 (wighteone) and 6-isopentenyl-2′-hydroxygenistein 4 (luteone), respectively.
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