Cyclic diguanylic acid stimulates 1,4-μ-glucan synthase from Saprolegnia monoica |
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| Authors: | Vincent Girard,Michel Fevre,Raphaë l Mayer,Moshe Benziman |
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| Affiliation: | Laboratoire de Biologie Cellulaire Fongique, Centre de Génétique Moléculaire et Cellulaire, UniversitéLyon 1, Villeurbanne, France;Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel |
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| Abstract: | Abstract: 1,4-μ-Glucan synthase activity, but not 1,3-μ-glucan-synthase activity, from Saprolegnia monoica was stimulated by cyclic-diguanylic acid, an immediate activator of Acetobacter xylinum - cellulose synthase. This activator, which increased the V max without modifying the K m for UDP-glucose, was active on solubilized and partially purified enzymes. These results suggest that the fungal system shares a common regulatory mechanism with the bacterial system. |
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| Keywords: | 1,4-μ Glucan synthase Saprolegnia monoica Cyclic diguanylic acid |
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