Synthesis of selected aminodeoxy analogs of globotriosylceramide |
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Authors: | Hansen H C Magnusson G |
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Affiliation: | Center for Chemistry and Chemical Engineering, Lund University, Sweden. |
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Abstract: | Four aminodeoxy analogs of globotriosylceramide (6"-, 4"-, 2"-, and 6'-aminodeoxy) were synthesized by glycosylation of 3-O-benzoylated azidosphingosine with the corresponding aminodeoxy-globotriose trichloroacetimidate, followed by reduction of the azido group, N-acylation with 1-adamantaneacetic acid, and removal of the protecting groups. |
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