| 异二聚体介导的mRNA核输出机制 |
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| 引用本文： | 郭晓强,王江雁. 异二聚体介导的mRNA核输出机制[J]. 生物技术通讯, 2006, 17(1): 99-100 |
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| 作者姓名： | 郭晓强 王江雁 |
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| 作者单位： | 解放军白求恩军医学院生化教研室,河北,石家庄,050081 |
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| 摘 要： | 真核生物mRNA在细胞核内被转录,而到达细胞质内翻译成为蛋白质,因此跨越核孔的核输出过程是必须的。现在已确定异二聚体TAP/NXT(在酵母中为Mex67p/Mtr2p)在此过程中是最基本的元件,此外其他相关因子如Aly、UAP56等也参与了这个复杂的过程,包括结合、输出、解离和载体输入。本文简要介绍了mRNA输出的基本机制。
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| 关 键 词： | mRNA 输出 异二聚体 |
| 文章编号： | 1009-0002（2006）01-0099-02 |
| 收稿时间： | 2005-06-20 |
| 修稿时间： | 2005-06-20 |
Mechanism on Heterodimers Mediated mRNA Export |
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| GUO Xiao-qiang,WANG Jiang-yan. Mechanism on Heterodimers Mediated mRNA Export[J]. Letters in Biotechnology, 2006, 17(1): 99-100 |
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| Authors: | GUO Xiao-qiang WANG Jiang-yan |
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| Abstract: | Eukaryotic mRNAs are transcribed in cell nuclear and exported to cytoplasm to translated into protein so it is essential for mRNAs to span nuclear pore. It is confirmed that heterodimers TAP/NXT Mex67p/Mtr2p in yeast are basic elements and other related factors also involved in this process. such as Aly UAP56. Export of mRNA is complex process including association export of mRNA dissociation import of carrier. In this article mechanism of mRNAs export was chiefly elucidated. |
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| Keywords: | mRNA export heterodimer |
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