Use of transcutaneous nerve stimulation in the attacks of acute intermittent porphyria |
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| Authors: | B Kaada I Romslo |
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| Affiliation: | 1. State Key Laboratory of Nuclear Resources and Environment, East China University of Technology, Nanchang 330013, China;2. School of Earth Sciences, East China University of Technology, Nanchang 330013, China;3. Jiangxi Engineering Laboratory on Radioactive Geoscience and Big Data Technology, East China University of Technology, Nanchang 330013, Jiangxi, China;4. Key Laboratory of Metallogenic Prediction of Nonferrous Metals and Geological Environment Monitoring, Ministry of Education, School of Geosciences and Info-Physics, Central South University, Changsha 410083, China |
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| Abstract: | A 38-year-old female with acute intermittent porphyria (AIP) was having regular recurrent premenstrual severe attacks of abdominal and chest pain due to the disease. Low-frequency transcutaneous nerve stimulation (TNS) premenstrually prevented or markedly reduced the severity of clinical attacks, associated with a reduced urinary porphyrin excretion. The possible mechanisms of the TNS-induced effects are discussed. This experience suggests that TNS may be an effective and simple prophylactic method in the management of the attacks in AIP. The method can be administered easily by the patient himself as home-treatment and is free of side-effects. |
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