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FASMA: A Service to Format and Analyze Sequences in Multiple Alignments
Authors:Susan Costantini Giovanni Colonna Angelo M Facchiano
Institution:Laboratory of Bioinformatics and Computational Biology, Institute of Food Science, CNR, via Roma 52 A/C,83100 Avellino, Italy;CRISCEB, Research Center of Computational and Biotechnological Sciences, Second University of Naples, via Costantinopoli 16, 80138 Naples, Italy CRISCEB, Research Center of Computational and Biotechnological Sciences, Second University of Naples, via Costantinopoli 16, 80138 Naples, Italy Laboratory of Bioinformatics and Computational Biology, Institute of Food Science, CNR, via Roma 52 A/C,83100 Avellino, Italy;CRISCEB, Research Center of Computational and Biotechnological Sciences, Second University of Naples, via Costantinopoli 16, 80138 Naples, Italy
Abstract:Multiple sequence alignments are successfully applied in many studies for under- standing the structural and functional relations among single nucleic acids and pro- tein sequences as well as whole families. Because of the rapid growth of sequence databases, multiple sequence alignments can often be very large and difficult to visualize and analyze. We offer a new service aimed to visualize and analyze the multiple alignments obtained with different external algorithms, with new features useful for the comparison of the aligned sequences as well as for the creation of a final image of the alignment. The service is named FASMA and is available at http: //bioinformatica.isa.cnr.it /FASMA /.
Keywords:multiple alignment  sequence analysis  web tools
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