| Abstract: | Intestinal obstruction occurring in human diseases or produced surgically in animal studies can produce fluid accumulation and intestinal distention. It was found that a quantitative theory for acute intestinal fluid accumulation could be derived and verified for a variety of experimental model systems. The contribution of intestinal secretagogues and distention-induced secretion may augment fluid accumulation in closed loop fluid accumulation experiments in animals. Criteria for stability and decompression of lumen volume were derived. |
