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The synthesis of 19-norandrostenedione from dehydroepiandrosterone in equine placenta is inhibited by aromatase inhibitors 4-hydroxyandrostenedione and fadrozole |
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| Authors: | Safa Moslemi Pierre Silberzahn Jean-Luc Gaillard |
| Institution: | Laboratoire de Biochimie, Centre National de la Recherche Scientifique URA 609, Université de Caen, France |
| Abstract: | 19-Norandrostenedione was synthesized in vitro from dehydroepiandrosterone by explants of equine full-term placenta. The synthesis of 19-norandrostenedione was inhibited by two specific aromatase inhibitors, 4-hydroxyandrostenedione and fadrozole. |
| Keywords: | Aromatase Dehydroepiandrosterone Equine Fadrozole 4-Hydroxyandro-stenedione Inhibition 19-Norandrostenedione Placenta |
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