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APE1 promotes embryonic stem cell proliferation and teratoma formation by regulating GDNF/GFRα1 axis
Institution:1. Department of Pathology, Childern’s Hospital of Hebei Province, Shijiazhuang, Heibei 050031, China;2. Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050004, China;3. Department of General Surgery, Childern’s Hospital of Hebei Province, Shijiazhuang, Heibei 050031, China;1. Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang 150086, PR China;2. North Translational Medicine Research Cooperation Center, 2019 Research Unit 070, Harbin, Heilongjiang 150086, PR China;3. The Department of Histology and Embryology, Harbin Medical University, Harbin 150086, PR China;4. The Department of Hepatopancreatobility, Surgery Second Affiliated Hospital of Harbin Medical University, 150086, PR China;1. Laboratory of Physiology and Toxicology of Reproduction, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Gronostajowa 9, 30-387 Krakow, Poland;2. Department of Animal Nutrition and Biotechnology, and Fisheries, Faculty of Animal Science, University of Agriculture in Krakow, al. Mickiewicza 21, 31-120 Krakow, Poland;1. Department of Molecular Endocrinology, National Institute for Research in Reproductive and Child Health, Indian Council of Medical Research, J.M. Street, Parel, Mumbai 400012, India;2. P. D. Hinduja National Hospital and Medical Research Centre, Mahim, Mumbai 400016, India;1. Department of Mesenchymal Stem Cells, Academic Center for Education, Culture, and Research (ACECR), Qom Branch, Qom, Iran;2. Department of Reproductive Biology, Academic Center for Education, Culture, and Research (ACECR), Qom Branch, Qom, Iran;3. Midwifery ward, Infertility treatment center, Academic Center for Education, Culture, and Research (ACECR), Qom Branch, Qom, Iran;1. Department of Forensic Medicine, Xinxiang Medical University, Xinxiang, Henan Province 453003, People’s Republic of China;2. Reproductive Physiology Laboratory, National Research Institute for Family Planning, Beijing 100081, People’s Republic of China;3. Graduate School of Peking Union Medical College, Beijing 100730, People’s Republic of China;4. Male Clinical Laboratory, National Research Institute for Family Planning, Beijing 100081, People’s Republic of China;5. Department of Cell Biology, Zunyi Medical University, Zunyi 563099, People’s Republic of China;6. Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, People’s Republic of China;1. Celal Bayar University, Faculty of Medicine, Department of Pediatrics, Division of Pediatric Endocrinology and Metabolism, Manisa, Turkey;2. Celal Bayar University, Faculty of Medicine, Department of Radiology, Manisa, Turkey;3. Ege University, Faculty of Medicine, Department of Pediatrics, ?zmi?r, Turkey;4. Celal Bayar University, Faculty of Medicine, Department of Clinical Biochemistry, Manisa, Turkey;5. Celal Bayar University, Faculty of Medicine, Department of Public Health, Mani?sa, Turkey;6. ?stinye University, School of Medicine, Department of Pediatrics, Division of Neonatalogy, ?stanbul, Turkey
Abstract:
Keywords:Embryonic stem cells  APE1  Pluripotency  Differentiation  GDNF  GFRα1
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