NIR spectroscopic imaging to map hemoglobin + myoglobin oxygenation,their concentration and optical pathlength across a beating pig heart during surgery |
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| Authors: | Eugene Gussakovsky Yanmin Yang John Rendell Olga Jilkina Valery Kupriyanov |
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| Institution: | 1. National Research Council Institute for Biodiagnostics, 435 Ellice Ave., Winnipeg, Manitoba, Canada R3B 1Y6;2. Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada R3E 3P5 |
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| Abstract: | The purpose of this paper is to demonstrate that near‐infrared (NIR) spectroscopic imaging can provide spatial distribution (maps) of the absolute concentration of hemoglobin + myoglobin, oxygen saturation parameter and optical pathlength, reporting on the biochemico‐physiological status of a beating heart in vivo. The method is based on processing the NIR spectroscopic images employing a first‐derivative approach. Blood‐pressure‐controlled gating compensated the effect of heart motion on the imaging. All the maps are available simultaneously and noninvasively at a spatial resolution in the submillimeter range and can be obtained in a couple of minutes. The equipment has no mechanical contact with the tissue, thereby leaving the heart unaffected during the measurement. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim) |
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| Keywords: | NIR spectroscopic imaging pig heart in vivo hemoglobin + myoglobin oxygenation and concentration optical pathlength |
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