Trypanosoma gambiense: Blocking ability of parasite and macrophage homogenates on attachment during phagocytosis

This study deals with the ability of the parasite and macrophage homogenates, each fractionated into soluble and insoluble parts, to block the attachment of Trypanosoma gambiense on the macrophage in the process of phagocytosis. The soluble parasite fraction and the insoluble macrophage fraction both showed a high blocking ability. However, the ability of the parasite fraction was completely lost on trypsin digestion, while that of the macrophage was not changed at all. In addition, sonication of the macrophage did not change its blocking ability.