Serological relationship of nuclear polyhedrosis viruses: I. Hemagglutination by polyhedral inclusion body protein from the nuclear polyhedrosis virus of Porthetria (= Lymantria) dispar

Polyhedral inclusion body protein (PIBP), harvested from the nuclear polyhedrosis virus (NPV) infecting the gypsy moth, Porthetria dispar, illicits the hemagglutination of chicken erythrocytes. Antisera to PIBP, polyhedral inclusion bodies (PIB), and virions (RODS) from the NPV's infecting P. dispar and the European Pine Sawfly, Neodiprion sertifer, inhibits hemagglutination when utilized to neutralize the PIBP from P. dispar. The crossreactivity of antisera to viral components from N. sertifer, a hymenopteran insect, with viral antigens from P. dispar, a lepidopteran insect, demonstrates a serological relationship exists between two viruses which have widely separated host ranges.