Endocytosis: an assembly protein for clathrin cages. |
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| Authors: | H T McMahon |
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| Affiliation: | MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK. |
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| Abstract: | The protein AP180 is known to have clathrin-assembly activity in vitro. AP180 has now been found to be crucial for synaptic vesicle endocytosis and the maintenance of a uniform-size vesicle population in vivo. These results significantly advance our understanding of clathrin-mediated endocytosis in the synapse and elsewhere. |
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