Deciphering the finger Prints of Brain Cancer Astrocytoma in comparison to Astrocytes by using near infrared Raman Spectroscopy |
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Authors: | Hirendra nath Banerjee L Zhang |
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Institution: | (1) Department of Biological Sciences, Elizabeth City State University, University of North Carolina, Elizabeth City, NC 27909, USA;(2) Department of Physics and Chemistry, Elizabeth City State University, University of North Carolina, Elizabeth City, NC 27909, USA |
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Abstract: | To explore the biochemical differences between brain cancer cells Astrocytoma and normal cells Astrocyte, we investigated
the Raman spectra of single cell from these two cell types and analyzed the difference in spectra and intensity. Raman spectrum
shows the banding pattern of different compounds as detected by the laser. Raman intensity measures the intensity of these
individual bands.
The Raman spectra of brain cancer cells was similar to those of normal cells, but the Raman intensity of cancer cells was
much higher than that of normal cells.
The Raman spectra of brain cancer Astrocytoma shows that the structural changes of cancer cells happen so that many biological
functions of these cells are lost. The results indicate that Raman spectra can offer the experimental basis for the cancer
diagnosis and treatment. |
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Keywords: | Raman spectroscopy Astrocytoma cancer optical tweezers |
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