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Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells
Authors:Peter Ghosh  Jiehua Wu  Susan Shimmon  Andrew CW Zannettino  Stan Gronthos  Silviu Itescu
Affiliation:(1) Proteobioactives Pty Ltd, 27/9 Powells Road, Brookvale, New South Wales, 2100, Australia;(2) Mesoblast Ltd, Level 39, 55 Collins Street, Melbourne, Victoria, 3000, Australia;(3) Myeloma Research Laboratory, Centre for Cancer Biology, Division of Haematology, Hansen Institute and Institute of Medical and Veterinary Science, Frome Road, Adelaide, South Australia, 5000, Australia;(4) Mesenchymal Stem Cell and Regenerative Medicine Group, Bone and Cancer Laboratories, Division of Haematology, Hansen Institute and Institute of Medical and Veterinary Science, Frome Road, Adelaide, South Australia, 5000, Australia
Abstract:

Introduction  

This study was undertaken to determine whether the anti-osteoarthritis drug pentosan polysulfate (PPS) influenced mesenchymal precursor cell (MPC) proliferation and differentiation.
Keywords:
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