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昂立植物乳杆菌粘附肠上皮细胞的研究
引用本文:范小兵,周丛,杭晓敏,沙大年. 昂立植物乳杆菌粘附肠上皮细胞的研究[J]. 中国微生态学杂志, 2004, 16(6): 353-355
作者姓名:范小兵  周丛  杭晓敏  沙大年
作者单位:上海交大昂立股份有限公司,生物医药研究所,上海,200233
摘    要:目的研究益生菌粘附肠上皮细胞机制,探讨益生菌的生物屏障机制,筛选益生菌.方法研究昂立植物乳杆菌(LP-Onlly)培养上清液,对病原菌和自身菌粘附Lovo细胞的影响.结果培养12 h的LP-Onlly发酵上清液在一定程度上能抑制病原菌的粘附,同时耗尽培养上清液,有促进自身菌粘附的作用.结论耗尽培养上清液中存在粘附素成分,能介导该菌的粘附.

关 键 词:植物乳杆菌  益生菌  粘附  病原菌  肠上皮细胞
文章编号:1005-376X(2004)06-0353-03
修稿时间:2004-05-25

Study on the adhesion of Lactobacillus plantarum LP-Onlly to cultured Lovo cell
FAN Xiao-bing,ZHOU Cong,HANG Xiao-min,et al.. Study on the adhesion of Lactobacillus plantarum LP-Onlly to cultured Lovo cell[J]. Chinese Journal of Microecology, 2004, 16(6): 353-355
Authors:FAN Xiao-bing  ZHOU Cong  HANG Xiao-min  et al.
Abstract:The study showed that the LP-Onlly culture could influence the adhesion of itself and pathogens to the cultured Lovo cells.The supernatant of the 12 h culture can partly prevent the attachment of pathogens,however,the spent supernatant of the culture could promote the adhesion of LP-Onlly to the cells.The study suggested an adhesion-promoting factor which was present in the spent supernatant could mediate LP-Onlly adhesion.
Keywords:L.plantarum  Probiotics  Adhesion  Pathogen  Lovo cell
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