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| 肉桂醛、柠檬醛对烟曲霉色素及关键基因alb1mRNA表达的影响 | |
| 引用本文： | 龙凯,谢小梅,方建如,旷雅舒. 肉桂醛、柠檬醛对烟曲霉色素及关键基因alb1mRNA表达的影响[J]. 微生物学通报, 2007, 34(3): 0541-0544 |
| 作者姓名： | 龙凯 谢小梅 方建如 旷雅舒 |
| 作者单位： | 1. 江西中医学院药学系,南昌,330004 2. 江西中医学院现代中药制剂教育部重点实验室,南昌,330004 3. 南昌大学生命科学院,南昌,330047 |
| 摘 要： | 研究了肉桂醛、柠檬醛对烟曲霉色素及其关键基因alb1 mRNA表达的影响。结果表明随着肉桂醛、柠檬醛浓度的增加,菌苔逐渐变稀、薄且烟绿色色素逐渐变淡,甚至白化;肉桂醛、柠檬醛对alb1基因mRNA表达有明显抑制作用,随着药物浓度的降低这种抑制作用亦相应呈现不同程度的减弱,肉桂醛、柠檬醛可能通过抑制alb1 mRNA的表达导致烟曲霉缺失烟绿色色素。 |
| 关 键 词： | 肉桂醛 柠檬醛 烟曲霉色素 |
| 文章编号： | 0253-2654（2007）03-0541-04 |
| 修稿时间： | 2006-09-29 |
The Influence of Cinnamldehyde and Citral on the Pigmentand the mRNA Expression of alb1 Gene of Aspergillus fumigatus |
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| LONG Kai,XIE Xiao-Mei,FANG Jian-Ru and KUANG Ya-Shu. The Influence of Cinnamldehyde and Citral on the Pigmentand the mRNA Expression of alb1 Gene of Aspergillus fumigatus[J]. Microbiology China, 2007, 34(3): 0541-0544 | |
| Authors: | LONG Kai XIE Xiao-Mei FANG Jian-Ru KUANG Ya-Shu |
| Affiliation: | 1. The Department of Pharmacy of Jiangxi Chinese Medical University, Nanehang 330004;2. Key Laboratory of Modern Preparation of TCM of Ministry of Education, Jiangxi Chinese Medical University, Nanehang 330004; 3. College of life Science, Nanehang University, Nanehang 330047 |
| Abstract: | The influence of the active ingredients of citral and cinn on the pigment and the mRNA expressions of alb1 gene of Aspergillus fumigatus were studied.Results indicated that in Czapak' s solid culture medium,the higher the concentration of ingredient was,the thinner the lawn would be,and the pigment became lighter and lighter gradually,even white;citral and cinn could obviously repress the expressions of alb1 gene and this effect was weakened by lower concentrations,The two can avaliably suppress the mRNA expression of alb1 gene which is essential for the biosynthesis of Aspergillus fumigatus's pigment. |
| Keywords: | RT-PCR |
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