High resolution, on-line identification of strains from the Mycobacterium tuberculosis complex based on tandem repeat typing |
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| Authors: | Philippe Le Flèche Michel Fabre France Denoeud Jean-Louis Koeck Gilles Vergnaud |
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| Affiliation: | (1) Centre d'Etudes du Bouchet BP3, 91710 Vert le Petit, France;(2) GPMS, Bt. 400, Institut de Gntique et Microbiologie, Universit Paris Sud, 91405 Orsay cedex, France;(3) Laboratoire de Biologie Clinique, HIA Percy, 92141 Clamart, France;(4) Dpartement de biologie mdicale, HIA Val-de-Grce, 75230 Paris, France |
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| Abstract: | Background Currently available reference methods for the molecular epidemiology of the Mycobacterium tuberculosis complex either lack sensitivity or are still too tedious and slow for routine application. Recently, tandem repeat typing has emerged as a potential alternative. This report contributes to the development of tandem repeat typing for M. tuberculosis by summarising the existing data, developing additional markers, and setting up a freely accessible, fast, and easy to use, internet-based service for strain identification. |
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