(1) Institute for Systems Biology, 1441 N. 34th Street, Seattle, WA 98103, USA;(2) Institut Pasteur, 25–28 Rue du Dr. Roux, 75724 Paris CEDEX 15, France
Abstract:
Background
The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological
information. The importance of integrating experimental data sets with molecular interaction networks has been recognized
and applied to the study of model organisms, but its systematic application to the study of human disease has lagged behind
due to the lack of tools for performing such integration.