从临床感染中分离的九株粘质沙雷氏菌

从临床化脓性感染中分离到九株革兰氏阴性产生脂溶性红色素的小杆菌。经详细鉴定(20种生化反应,120种底物利用试验及G+C mol%测定)为粘质沙雷氏菌(Serratia marcescens)。其中两株能利用3,4-二羟基苯甲酸盐为唯一的碳源而生长,证明此试验适用于本属的种型鉴定。9株菌中有7株细菌属于粘质沙雷氏菌A₂型。药敏试验显示青霉素及其它作用于细胞壁的抗生素对这些菌无效而所试验的氨基糖苷类抗生素几乎全有效。红霉紊、链霉素和复方增效磺胺则各株间的敏感性不同;磺胺虽

NINE STRAINS OF SERRATIA MARCESCENS ISOLATED FROM CLINICAL SAMPLES

Nine strains of Serratia rnarcescens were isolated from clinical samples. In the identification, 20 items of biochemical reactions and 124 items of substrate utilization tests have been used. Two strains, which have not been appointed to a biotype of the species, can utilize 3-hydroxybenzoate, 4-hydroxybenzoate or protoeatechuate as sole carbon source for growth. The growth in protocatechuate medium was more rapid as compared with 3 or 4-hydroxybenzoate medium. So, we here suggest that protocatechuate should be included in the substrate utilization for the genus. The other seven strains have been identified as Grimont' s A_2 subphenon of S. marcescens. Pencillin and other wall-acting antibiotics are all resisted by these strains; aminoglycoside antibiotics are almost all effective. Co-trimoxazole and sulfadiazine, though couldn't inhibite the growth of the strains, do inhibite their pigment production.