| Abstract: | The localization, structure, and activity of the nucleolus-organizers (NORs) were studied during spermiogenesis in the mouse by light and electron microscopy procedures including NOR-silver-staining and actinomycin D treatment. After the two meiotic divisions the NORs resume their activity during the Golgi phase of spermatid differentiation (steps 1-3), and the nucleolus displays a specific 'padlock' structure containing the fibrillar components of an active nucleolus. This activity drops during the cap phase (steps 4-7) during which the nucleolus undergoes a segregation process of its components. No nucleolar structure is visible during the acrosomal and maturation phases of spermatid differentiation. |
