Newly identified genetic variations in common Escherichia coli MG1655 stock cultures |
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Authors: | Freddolino Peter L Amini Sasan Tavazoie Saeed |
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Institution: | Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA. |
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Abstract: | We have recently identified seven mutations in commonly used stocks of the sequenced Escherichia coli strain MG1655 which do not appear in the reference sequence. The mutations are likely to cause loss of function of the glpR and crl genes, which may have serious implications for physiological experiments using the affected strains. |
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