Daphnia magna, a host for evaluation of bacterial virulence |
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Authors: | Le Coadic Marion Simon Marianne Marchetti Anna Ebert Dieter Cosson Pierre |
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Institution: | Université de Genève, Centre Médical Universitaire, Département de Physiologie Cellulaire et Métabolisme, Genèva, Switzerland. |
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Abstract: | We show that Daphnia magna can be used to assess acute virulence of pathogens relevant to human health, such as Pseudomonas aeruginosa or Photorhabdus asymbiotica. Analysis of bacterial mutants suggests that P. aeruginosa uses similar mechanisms to infect Daphnia and other hosts. |
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