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乳杆菌泡腾片治疗细菌性阴道病
引用本文:刘京,陈彬华,程丛娟,曾红,王文风.乳杆菌泡腾片治疗细菌性阴道病[J].中国微生态学杂志,2007,19(1):61-62.
作者姓名:刘京  陈彬华  程丛娟  曾红  王文风
作者单位:1. 上海医药(集团)有限公司信谊制药总厂,上海,200071
2. 复旦大学附属妇产科医院
3. 复旦大学药学院
摘    要:目的观察10例BV患者采用了信谊制药总厂生产的阴道嗜酸乳杆菌泡腾片1个疗程(7 d)后阴道菌群的变化。方法采用7种选择或非选择培养基对阴道分泌物的细菌总数、乳杆菌等7个指标进行检测。结果治疗后阴道中乳杆菌显著增多,厌氧革兰阴性杆菌显著减少(两者P<0.001)。细菌总数、肠杆菌、酵母菌和阴道加德纳菌均减少(P<0.01)。结论信谊阴道嗜酸乳杆菌泡腾片具有较好的调整阴道微生态平衡的作用。

关 键 词:嗜酸乳杆菌  泡腾片  细菌性阴道病  阴道菌群
文章编号:1005-376X(2007)01-0061-02
收稿时间:2006-05
修稿时间:2006年5月1日

Research on bacterial flora of vagina in bacterial vaginosis patients by Lactobacillus acidphillus effervescent tablet
LIU Jing,CHEN Bin-hua,CHENG Cong-juan,ZENG Hong,WANG Wen-feng.Research on bacterial flora of vagina in bacterial vaginosis patients by Lactobacillus acidphillus effervescent tablet[J].Chinese Journal of Microecology,2007,19(1):61-62.
Authors:LIU Jing  CHEN Bin-hua  CHENG Cong-juan  ZENG Hong  WANG Wen-feng
Institution:1. Sine Pharmaceutical Laboratories, Shanghai Pharmaceutical ( group
Abstract:Objective To ivestigate the change of vaginal bacterial flora in 10 patients with bacterial vaginosis(BV) by Lactobacillus acidphillus effervescent for 1 course of treatment(7 days).Methods 7 indexes that were the sum of bacteria,the number of lactobacillus,anaerobic Gram's negative bacilli and other bacterial species were examined in vaginal secretion by seven kinds of selected or non-selected media.Results After treatment,the number of Lactobdcillus was increased markedly in vaginal secretion,while anaerobic Gram's negative bacilli was decreased markedly,both P<0.001,the sum of bacteria,enterobacillus,yeast and Gardnerella vaginalis were decresed,P<0.01.Conclusion The microecosystem of vaginal bacterial flora can be well balanced by Lactobacillus acidphillus effervescent tablets produced by SPGC Sine Pharma Laboratories.
Keywords:Lactobacillus acidphillus  Effervescent tablet  Bacterial vaginosis  Bacterial flora of vagina
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