Inverted papilloma of the nasal cavity presenting with massive amounts of squamous metaplastic cells in sputum. A case report |
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Authors: | Yamazaki Koichi Furuta Yasushi Marukawa Katsuji Moriya Jun Shimizu Mikio Arakawa Mikio Itoh Tomoo Shimizu Michio Fukumoto Shinichi Ogura Shigeaki Dosaka-Akita Hirotoshi Nishimura Masaharu |
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Institution: | First Department of Medicine, Hokkaido University School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan. |
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Abstract: | BACKGROUND: Squamous metaplasic cells are rarely seen in sputum of female nonsmokers. CASE: A 47-year-old female nonsmoker presented with massive amounts of squamous metaplasic cells in sputum and an elevated level of squamous cell carcinoma (SCC) antigen in serum present for months, while no causative lesion was detected either by lung computed tomography or bronchoscopy. The patient was eventually diagnosed as having inverted papilloma in the right nasal cavity. Resection of the tumor brought about disappearance of squamous metaplastic cells in sputum and return of serum SCC antigen to the normal range. CONCLUSION: This case clearly demonstrates that squamous metaplastic cells in sputum can originate in lesions in the nasal cavity, although they are rare. It should be kept in mind that the nasal cavity is a potential site producing squamous metaplastic cells in sputum. |
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