2',3'-isopropylidene group, a molecular scaffold to study the activity of adenosine and adenylate deaminase on adenosine analogues modified in the ribose moiety |
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| Authors: | Ciuffreda Pierangela Alessandrini Laura Santaniello Enzo |
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| Affiliation: | Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, via G.B. Grassi 74, 20157 Milan, Italy. pierangela.ciuffreda@unimi.it |
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| Abstract: | 2 ',3 '-Isopropylidene group can be used as a molecular scaffold for the introduction of modifications at 5 ' and 1 ' positions of adenosine and these modified nucleosides are used to evaluate the biocatalytic activity of adenosine and adenylate deaminase. |
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