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The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α
Authors:Michela Guglielmotto  Manuela Aragno  Riccardo Autelli  Luca Giliberto†  Erica Novo  Sebastiano Colombatto  Oliviero Danni  Maurizio Parola  Mark A Smith‡  George Perry§  Elena Tamagno¶  Massimo Tabaton†
Institution:Department of Experimental Medicine and Oncology, University of Turin, Turin, Italy;
Department of Neurosciences, University of Genoa, Genoa, Italy;
Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA;
College of Sciences, University of Texas at San Antonio, San Antonio, Texas, USA;
Centro Interdipartimentale di Studi Avanzati in Neuroscienze, University of Turin, Turin, Italy
Abstract:
Keywords:Alzheimer' disease  β-site APP cleaving enzyme  hypoxia inducible factor 1α  hypoxia  neuroblastoma cells  oxidative stress
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