| 小刺猴头菌发酵浸膏寡糖对荷瘤小鼠免疫功能的影响 |
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| 引用本文： | 杜金,胡静,隋玉龙,杨杨,吴宗翰,宋慧.小刺猴头菌发酵浸膏寡糖对荷瘤小鼠免疫功能的影响[J].菌物研究,2013,11(2):116-119. |
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| 作者姓名： | 杜金 胡静 隋玉龙 杨杨 吴宗翰 宋慧 |
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| 作者单位： | 1. 吉林农业大学生命科学学院,长春,130118
2. 吉林农业大学生命科学学院,长春130118;吉林农业大学教育部食药用菌工程研究中心,长春130118 |
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| 基金项目： | 吉林省世行贷款农产品质量安全项目，长江学者和创新团队计划项目 |
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| 摘 要： | 通过建立S180荷瘤小鼠试验动物模型,研究小刺猴头菌发酵浸膏寡糖对S180荷瘤小鼠免疫功能的影响。选择灌胃的方法将不同组别小刺猴头菌发酵浸膏寡糖喂服到荷瘤小鼠体内,观察肿瘤生长情况,对其进行免疫功能的测定。结果表明:小刺猴头菌发酵浸膏寡糖可增加荷瘤小鼠免疫器官脾脏和胸腺质量,提高荷瘤小鼠血清的IL-2和TNF-α含量,抑制肿瘤生长,提高机体免疫功能。
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| 关 键 词： | 小刺猴头菌 寡糖 荷瘤小鼠 免疫功能 |
Effect of Hericium caput-medusae Oligosaccharide on Immunity Function of Tumor Mice |
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| DU Jin,HU Jing,SUI Yu-long,YANG Yang,WU Zong-han,SONG Hui.Effect of Hericium caput-medusae Oligosaccharide on Immunity Function of Tumor Mice[J].Journal of Fungal Research,2013,11(2):116-119. |
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| Authors: | DU Jin HU Jing SUI Yu-long YANG Yang WU Zong-han SONG Hui |
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| Institution: | 1. College of Life Science, Jilin Agricultural University, Changchun 130118, China; 2. Engineering Research Center of Chinese Ministry of Education for Edible and Medicinal Fungi, Jilin Agricultural Uni- versity, Changchun 130118, China) |
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| Abstract: | By establishing tumor animal model of $180 tumor mice, the effect of Hericium caput-medusae oligosaccharide on immunity function of tumor mice was studied. Tumor growth was observed after differ- ent kinds of Hericium caput-medusae oligosaccharide were fed to the mice, then immunity function was measured. Hericium caput-medusae oligosaccharide can increase the content of IL-2 and TNF-α in serum and the weight of mice spleen and thymus, inhibit tumor growth and improve immunity function. |
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| Keywords: | Hericium caput-medusae oligosaccharide tumor mice immunity function |
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