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Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells
Authors:Akinobu Matsumoto  Keiichi I. Nakayama
Affiliation:Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812‐8582, Japan; CREST, Japan Science and Technology Agency (JST), Kawaguchi, Saitama 332‐0012, Japan
Abstract:
Keywords:APC/C, anaphase-promoting complex/cyclosome   BM, bone marrow   CDK, cyclin-dependent kinase   CKI, cyclin-dependent kinase inhibitor   CXCL12, chemokine (C-X-C motif) ligand 12   HSC, hematopoietic stem cell   Hsc70, heat shock cognate protein 70   LAP, latency-associated protein   LLC, large latent complex   LTBP-1, latent transforming growth factor‐β binding protein‐1   Rb, retinoblastoma protein   SCF, Skp1&ndash  Cul1&ndash  F-box protein   TPO, thrombopoietin   TGF-β, transforming growth factor‐β
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