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Thyroid hormone receptors and cancer

Authors:	Won Gu Kim Sheue-yann Cheng

Institution:	Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA

Abstract:

Keywords:	BM basement membrane ECM extracellular membrane EMT epithelial mesenchymal transition FAK focal adhesion kinase MAPK mitogen-activated protein kinase LOH loss of heterozygosity NCOR1 nuclear receptor co-repressor 1 MMP matrix metalloproteinase mTOR mammalian target of rapamycin PAX8 paired box gene 8 PIP2 phosphatidylinositol-4 5-biphosphate PIP3 phosphatidylinositol-3 4 5-triphosphate PI3K phosphatidylinositol 3-kinase PPARγ peroxisome proliferator-activated receptor γ PPRE peroxisome proliferator responsive element PPTG pituitary tumor-transforming gene PTEN phosphatase and tensin homologue deleted from chromosome 10 RTH resistance to thyroid hormone RXRα retinoid X receptor α SH Src homology SKY spectral karyotyping analysis SMRT silencing mediator of retinoid and thyroid hormone receptors SRC steroid receptor co-activator TREs thyroid hormone response elements TRs thyroid hormone nuclear receptors T3 triiodothyronine TSH thyroid stimulating hormone
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