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Identification of a highly potent vitamin D receptor antagonist: (25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3) |
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| Authors: | Igarashi Miharu Yoshimoto Nobuko Yamamoto Keiko Shimizu Masato Ishizawa Michiyasu Makishima Makoto DeLuca Hector F Yamada Sachiko |
| Institution: | School of Biomedical Science, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan. |
| Abstract: | |
| Keywords: | Vitamin D receptor Partial agonist Antagonist Adamantyl vitamin D Chemical synthesis Biological activity Docking analysis Inhibition of transactivation |
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