Chromosome aberration in human lymphocytes after X-irradiation in vitro. II. Analysis of primary processes in the formation of dicentric chromosomes |
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| Authors: | M Bauchinger E Schmid |
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| Affiliation: | 1. Institut für Biologie der Gesellschaft für Strahlen- und Umweltforschung mbH und Strahlenbiologisches Institut der Universität München, 8 München 2, Bavariaring 19, W. Germany |
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| Abstract: | The rejoining distance for the formation of dicentric chromosomes in human lymphocytes has been derived on the basis of microdosimetric concepts. For the formation of a dicentric chromosome, primary lesions produced by absorption events can interact within the nucleus over a distance of at least 1 μm. The dispersion of dicentrics is near to 1 and corresponds to a site number between 17 and 120. |
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