培菌昆虫相关放线菌的次级代谢产物研究进展

昆虫共生微生物是一种特殊的微生物资源,其中放线菌在昆虫肠道、体表和巢穴中广泛分布。近年来,人们从培菌昆虫来源的放线菌中分离得到多种新型化合物,可以选择性抑制菌圃的致病真菌,部分还对植物致病真菌、昆虫致病真菌、人类病原菌和癌细胞有抑制活性。因此,研究培菌昆虫相关微生物不仅有助于了解宿主与微生物的共生机制,还能发掘新的活性物质,用于生物农药、生物医药的开发。本文对培菌昆虫来源放线菌次级代谢产物的研究进展进行了综述。

Research progress in secondary metabolites from fungus-growing insects associated actinomycetes

Insect symbiotic microbes are a group of special microbial resources. The actinomycetes widely exist in the insect intestines, cuticle or the nest. Some of fungus-growing insects associated actinomycetes can produce secondary metabolites that inhabit pathogenic microorganisms of the insects, plants or human tumor cells. Thus, the research on insect symbiotic actinomycetes not only can facilitate understanding of the symbiotic mechanism between insects and symbionts, but also explore new bioactive compounds for the development of biological pesticides and medicines. This review summarizes the advances in the study on the secondary metabolites from fungus-growing insects associated actinomycetes.