Codon usage in Pseudomonas aeruginosa. |
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| Authors: | S E West and B H Iglewski |
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| Affiliation: | Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, NY 14642. |
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| Abstract: | We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position. |
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