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Distinct genetic landscape and a low response to doxorubicin in a luminal-A breast cancer cell line of Pakistani origin |
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| Authors: | Shakeel Muhammad Khan Salman Ahmed Mughal Anum Jabeen Irfan Muhammad Hoessli Daniel C Choudhary M Iqbal Aurongzeb Muhammad Khan Ishtiaq Ahmad |
| Institution: | 1.Jamil-ur-Rahman Center for Genome Research, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, ICCBS, University of Karachi, Karachi, 75270, Pakistan ;2.Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan ;3.Department of Molecular Medicine, Dow College of Biotechnology, Dow University of Health Sciences, Karachi, Pakistan ;4.Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia ; |
| Abstract: | Molecular Biology Reports - Breast cancers exhibit genetic heterogeneity which causes differential responses to various chemotherapy agents. Given the unique demographic and genomic background in... |
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