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Development of a one-plasmid system to replace the endogenous protein with point mutation for post-translational modification studies |
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| Authors: | Ishrat Iqra Cheng Aoxing Yu Fazhi Guo Jing Zhang Peng Zhang Kaiguang Yang Zhenye |
| Affiliation: | 1.Department of Digestive Disease, The First Affiliated Hospital of USTC, Anhui Provincial Hospital, University of Science and Technology of China, Hefei, China ;2.Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China ;3.Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China ; |
| Abstract: | Molecular Biology Reports - Post-translational modification (PTM) is one of the major regulatory mechanism for protein activities. To understand the function of PTMs, mutants that prevent or mimic... |
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