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Expression and pharmacological inhibition of TrkB and EGFR in glioblastoma |
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| Authors: | Pinheiro Kelly V. Thomaz Amanda Souza Bárbara Kunzler Metcalfe Victoria Anne Freire Natália Hogetop Brunetto André Tesainer de Farias Caroline Brunetto Jaeger Mariane Bambini Victorio Smith Christopher G. S. Shaw Lisa Roesler Rafael |
| Affiliation: | 1.Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, RS, 90035-003, Brazil ;2.Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Rua Sarmento Leite, 500 (ICBS, Campus Centro/UFRGS), Porto Alegre, RS, 90050-170, Brazil ;3.Children’s Cancer Institute, Porto Alegre, RS, 90620-110, Brazil ;4.Faculty of Clinical and Biomedical Sciences, School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire, PR1 2HE, UK ; |
| Abstract: | Molecular Biology Reports - A member of the Trk family of neurotrophin receptors, tropomyosin receptor kinase B (TrkB, encoded by the NTRK2 gene) is an increasingly important target in various... |
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