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Nicotinamide mononucleotide and melatonin counteract myocardial ischemia-reperfusion injury by activating SIRT3/FOXO1 and reducing apoptosis in aged male rats
Authors:Jafari-Azad  Aida  Hosseini  Leila  Rajabi  Mojgan  Høilund-Carlsen  Poul Flemming  Vafaee   Manouchehr Seyedi  Feyzizadeh   Saeid  Badalzadeh   Reza
Affiliation:1.Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
;2.Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
;3.Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark
;4.Department of Clinical Research, University of Southern Denmark, Odense, Denmark
;5.Psychiatry Research Unit, Southern Denmark Region, Odense, Denmark
;6.Molecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
;7.Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
;
Abstract:Molecular Biology Reports - It has been documented that aging increases the risk of cardiovascular disease including myocardial ischemia/reperfusion (IR) injury and acute myocardial infarction. In...
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