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Inositol hexakisphosphate kinase 2 promotes cell death of anterior horn cells in the spinal cord of patients with amyotrophic lateral sclerosis
Authors:Nagata  Eiichiro  Fujii  Natsuko  Kohara  Saori  Okada  Chisa  Satoh  Tadayuki  Takekoshi  Susumu  Takao  Masaki  Mihara  Ban  Takizawa  Shunya
Institution:1.Department of Neurology, Tokai University School of Medicine, 143 Shimo-Kasuya, Isehara, Kanagawa, 259-1193, Japan
;2.Support Center for Medical Research and Education, Tokai University, Isehara, Japan
;3.Department of Clinical Pathology, Tokai University School of Medicine, Isehara, Japan
;4.Department of Clinical Laboratory, National Center of Neurology and Psychiatry (NCNP), National Center Hospital, Tokyo, Japan
;5.Department of Neurology, Mihara Memorial Hospital, Gunma, Japan
;
Abstract:Molecular Biology Reports - We have previously reported that inositol hexakisphosphate kinase (InsP6K)2 mediates cell death. InsP6K2 is abundantly expressed in anterior horn cells of the mammalian...
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