| 国产冻干水痘减毒活疫苗免疫原性研究与应用 |
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| 引用本文： | 王志军 王树巧. 国产冻干水痘减毒活疫苗免疫原性研究与应用[J]. 微生物学免疫学进展, 2000, 28(4): 17-18 |
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| 作者姓名： | 王志军 王树巧 |
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| 作者单位： | [1]扬州市广陵区卫生防疫站,扬州 [2]上海生物制品研究所,上海市 |
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| 摘 要： | 对１２９名４岁儿童采用国产、进口水痘减毒活疫苗进行免疫，对疫苗的安全性和免疫原性进行研究，用ＥＬＩＳＡ进行免前、免后水痘抗体测定。结果表明国产水痘疫苗接种后无明显副反应，国产、进口疫苗血清的阳转率相似，达８５％以上，证明国产ＯＫａ株水痘减毒活疫苗具有良好的安全性和免疫性，可以推广使用。
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| 关 键 词： | 水痘 水痘疫苗 免疫效果 免疫原性 |
Studies on safety and immunogenicity of lyophilized live attenuated Varicella vaccine |
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| WANG Zhi jun,QIAN Ying,ZHANG Yian,et al.. Studies on safety and immunogenicity of lyophilized live attenuated Varicella vaccine[J]. Progress In Microbiology and Immunology, 2000, 28(4): 17-18 |
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| Authors: | WANG Zhi jun QIAN Ying ZHANG Yian et al. |
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| Abstract: | year old children were vaccinated with lyophilized live attenuated varicella vaccines(Oka strain)from SIBP(Shanghai Institute of Biological Products)and BIKEN to determine their safety and immunogenicity.The antibody was determined with ELISA.The result showed that the Varicella vaccine from SIBP had no appearant adverse reaction,and that both vaccines from SIBP and BIKEN had high sero conversion rate,85.8% and 92% respectively.It showed that Varicella vaccine from SIBP is the same as BINKEN,which has high safety and good immunogenicity. |
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| Keywords: | Varicella Varicella vaccine Immune efficacy |
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