Mapping of the human C3G gene coding a guanine nucleotide releasing protein for Ras family to 9q34.3 by fluorescence in situ hybridization |
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| Authors: | Setsuo Takai Masamitsu Tanaka Haruhiko Sugimura Kiyomi Yamada Yasuhisa Naito Isamu Kino Michiyuki Matsuda |
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| Affiliation: | (1) Department of Genetics, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, 162 Tokyo, Japan;(2) 1st Department of Pathology, Hamamatsu University School of Medicine, 3600 Handa-cho, Hamamatsu, 431-31 Shizuoka, Japan;(3) Department of Pathology, National Institute of Health, 1-21-1, Toyama, Shinjuku-ku, 162 Tokyo, Japan |
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| Abstract: | C3G, a human guanine nucleotide releasing protein for Ras protein, was mapped to human chromosome 9q34.3 by fluorescence in situ hybridization with Rbanded chromosomes. C3G was originally identified as one of the CRK-binding proteins, similar to c-ab1 (9q34.1). Our result suggests that the downstream factors of Crk are localized in close proximity on chromosome 9. |
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