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Synthesis of a potential tetrasaccharide ligand for E-selectin
Authors:Qin Zhi Hui  Liu Hong  Li Hui  Cai Meng Shen  Li Zhong Jun
Affiliation:National Research Laboratory of Natural and Biomimetic Drugs, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100083, PR China.
Abstract:A potential tetrasaccharide ligand for E-selectin, (Na(+-)O(3)SO-3)Galbeta-(1-->4)[Fucalpha-(1-->3)]Glcbeta-(1-->6)Gal, an analogue of the ovarian cystadenoma glycoprotein tetrasaccharide fragment, was synthesized in a highly practical way.
Keywords:Potential selectin ligand   Tumor-related oligosaccharides   Oligosaccharide   Synthesis
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