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Regional localization of human M-BCR gene to chromosome 23 band q11 in the great apes
Authors:Rhea V Samonte  K H Ramesh  Ram S Verma
Institution:(1) Division of Genetics, The Long Island College Hospital, SUNY Health Science Center at Brooklyn, 11201, NY, USA
Abstract:We hybridized a human M-BCR DNA probe to the chromosomes of chimpanzee (Pan troglodytes), gorilla (Gorilla gorilld) and orangutan (Pongo pygmaeus) by FISH-technique. The human M-BCR gene was localized to chromosome 23 band q11 (23q11), which is equivalent to the human chromosome 22 band q11 in all three species. The conservation of M-BCR gene in higher primates at the corresponding human chromosome locus provides phylogenetic clues concerning the evolution of genes.
Keywords:chromosome 22  chimpanzee  gorilla  orangutan  M-BCR gene
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