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Study of the combined effects of PTH treatment and mechanical loading in postmenopausal osteoporosis using a new mechanistic PK-PD model
Authors:Lavaill  Maxence  Trichilo  Silvia  Scheiner  Stefan  Forwood  Mark R  Cooper  David M L  Pivonka  Peter
Institution:1.Biomechanics and Spine Research Group, Queensland University of Technology, Brisbane, QLD, Australia
;2.St Vincent’s Department of Surgery, University of Melbourne, Melbourne, VIC, Australia
;3.Institute for Mechanics of Materials and Structures, Vienna University of Technology (TU Wien), Vienna, Austria
;4.School of Medical Science, Griffith University, Gold Coast, QLD, Australia
;5.Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, Canada
;
Abstract:Biomechanics and Modeling in Mechanobiology - One of only a few approved and available anabolic treatments for severe osteoporosis is daily injections of PTH (1-34). This drug has a specific dual...
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