Importance de la qualité du sperme

The semen quality and sperm chromatin alteration have added a new dimension to the evaluation of male factors in repeated spontaneous abortion (RSA). The aim of the study was to evaluate the importance of the sperm quality in RSA conjugal partners. In RSA group, when husbands sperm having more 50% of normal forms and more 50% of native DNA, the paternal lymphocytes injection may lead to a positive immunization. However, no benefit of immunotherapy between conjugal partners if the conventional semen parameters and chromatin quality were altered. Our data indicates that among the vast array of male factors, sperm morphology and chromatin quality seems to be an important criterion to conceive or maintain pregnancy of women with a RSA.