Bis(monoterpenoid) indole alkaloid glucosides from Uncaria hirsuta |
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| Authors: | Wen-Bo Xin Gui-Xin Chou Zheng-Tao Wang |
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| Institution: | aKey Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201203, PR China;bShanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201203, PR China |
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| Abstract: | One novel bis(monoterpenoid) indole alkaloid glucoside, hirsutaside D (1), along with three known compounds, bahienoside A (2), bahienoside B (3) and neonaucleoside B (4), were isolated from the leaves of U. hirsuta. The structure of compound 1 was elucidated on the basis of extensive spectroscopic data analysis and chemical means. Characterization of compounds 2–4 was based on spectral analysis and comparison with the literature. Their cytotoxic effects on four human tumor cell lines were examined. |
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| Keywords: | Uncaria hirsuta Leaves Indole alkaloid glucosides |
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