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Metabolically Healthy Obesity and the Risk of Cardiovascular Disease in the Elderly Population
Authors:Klodian Dhana  Chantal M Koolhaas  Elisabeth F C van Rossum  M Arfan Ikram  Albert Hofman  Maryam Kavousi  Oscar H Franco
Abstract:BackgroundWhether being metabolically healthy obese (MHO)—defined by the presence of obesity in the absence of metabolic syndrome—is associated with subsequent cardiovascular disease (CVD) remains unclear and may depend on the participants’ age. We examined the association of being MHO with CVD risk in the elderly.ConclusionsIn our elderly population, we found that the presence of obesity without metabolic syndrome did not confer a higher CVD risk. However, metabolic syndrome was strongly associated with CVD risk, and was associated with an increased risk in all BMI categories. Therefore, preventive interventions targeting cardiometabolic risk factors could be considered in elderly, regardless of weight status.
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