Age-related changes of mineral contents in the human aorta and internal thoracic artery |
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Authors: | Yoshiytiki Tohno Setsuko Tohno Takeshi Minami Masako Utsumi Yumi Moriwake Fumio Nishiwaki Masa-oki Yamada Keizo Yamamoto Yasuo Takano Yuko Okazaki Hiroshi Yamamoto |
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Affiliation: | (1) Department of Anatomy, Laboratory of Cell Biology, Japan;(2) The 2nd Department of Anatomy, Nara Medical University, Kashihara, 634 Nara, Japan;(3) Department of Anatomy, Kochi Medical School, Nangoku, 783 Kochi, Japan;(4) Faculty of Pharmaceutical Sciences, Kinki University Higashi-Osaka, 577 Osaka, Japan |
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Abstract: | To elucidate accumulations of minerals in the human aorta and internal thoracic artery, their relative contents (RCs) of minerals were analyzed by inductively coupled plasma atomic emission spectrometry. Aortas from 47 men and 24 women subjects were examined. The ages of these subjects ranged from newborn to 99 yr. After the age of 40 yr, RCs of calcium and phosphorus began to increase, and thereafter increased stepwise in the 50s and 70s. In the 70s, their accumulations were markedly increased. Internal thoracic arteries from 16 men and 7 women subjects were examined. These subjects ranged in age from 65–93 yr. It was found that all the RCs of calcium were low, <5.0 mg/g dry wt, and there was no age-dependent increase of calcium contents in internal thoracic arteries. |
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Keywords: | Aorta internal thoracic artery calcium phos-phorus aging |
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